The American contribution to attachment theory:John Bowlby’s WHO trip to the USA in 1950 and the development of his ideas on separation and attachment

This paper explores John Bowlby’s foundational contributions to attachment theory, particularly his fascination with ‘separation’ and its impact on child development. Tracing the origins of Bowlby’s interest to his personal experiences and his exposure to ideas of mental hygiene and child guidance in the 1930s, it underscores the alignment of his ideas with key figures in the English school of psychoanalysis. The central narrative of this paper unfolds during Bowlby’s 1950 WHO research trip, investigating orphaned and separated children in Europe and the USA. Utilizing archival materials from the Wellcome Library in London, the authors offer unique insights into Bowlby’s journey, highlighting his evolving views on mother-child separation through interactions with his American colleagues. This comprehensive exploration sheds light on Bowlby’s pioneering work, emphasizing the American influence on his ideas, and the evolving theoretical framework that continues to shape our understanding of child development and attachment today.</p

The American contribution to attachment theory:John Bowlby’s WHO trip to the USA in 1950 and the development of his ideas on separation and attachment

This paper explores John Bowlby’s foundational contributions to attachment theory, particularly his fascination with ‘separation’ and its impact on child development. Tracing the origins of Bowlby’s interest to his personal experiences and his exposure to ideas of mental hygiene and child guidance in the 1930s, it underscores the alignment of his ideas with key figures in the English school of psychoanalysis. The central narrative of this paper unfolds during Bowlby’s 1950 WHO research trip, investigating orphaned and separated children in Europe and the USA. Utilizing archival materials from the Wellcome Library in London, the authors offer unique insights into Bowlby’s journey, highlighting his evolving views on mother-child separation through interactions with his American colleagues. This comprehensive exploration sheds light on Bowlby’s pioneering work, emphasizing the American influence on his ideas, and the evolving theoretical framework that continues to shape our understanding of child development and attachment today.</p

Noninvasive Assessment of Spatio-Temporal Recurrence in Atrial Fibrillation

Propagation of Atrial Activity during atrial fibrillation (AF) is a complex phenomenon characterized by a certain degree of recurrence (periodic repetition). In this study, we investigated the possibility to detect recurrence noninvasively from body surface potential map recordings in patients affected by persistent AF, and localize this recurrence both in time and space. Results showed that clusters of recurrence can be identified from body surface recordings in these patients. Moreover, the number of clusters detected and their location on the top-right of the back of the torso were significantly associated with AF recurrence 4 to 6 weeks after electrical cardioversion. This suggests that noninvasive quantification of recurrence in persistent AF patients is possible, and may contribute to improve patient stratification

The nature of love: Harlow, Bowlby and Bettelheim on affectionless mothers

Harry Harlow, famous for his experiments with rhesus monkeys and cloth and wire mothers, was visited by psychiatrist and psychoanalyst John Bowlby and by child psychologist Bruno Bettelheim in 1958. They made similar observations of Harlow’s monkeys, yet their interpretations were strikingly different. Bettelheim saw Harlow’s wire mother

Assembly and Functional Architecture of Bacterial Chemoreceptor Nanoarrays

Transmembrane chemotaxis receptors are found in bacteria in extended hexagonal arrays stabilized by the membrane and by cytosolic binding partners, the kinase CheA and coupling protein CheW. Models of array architecture and assembly propose receptors cluster into trimers-of-dimers that associate with one CheA dimer and two CheW monomers to form the minimal core unit necessary for signal transduction. Reconstructing in vitro chemoreceptor ternary complexes that are homogenous, functional, and exhibit native architecture remains a challenge. Here we report that His-tag mediated receptor dimerization with divalent metals is sufficient to drive assembly of native-like functional arrays of a receptor cytoplasmic fragment. Our results indicate receptor dimerization initiates assembly and precedes formation of ternary complexes with partial kinase activity. Restoration of maximal kinase activity coincides with a shift to larger complexes, suggesting that kinase activity depends on interactions beyond the core unit. We hypothesize that achieving maximal activity requires building core units into hexagons and/or coalescing hexagons into the extended lattice. This discovery may also address a previously observed density-dependent transition between signaling states. To further test this, we implemented a paramagnetic relaxation enhancement (PRE) based solid-state NMR approach to obtain long-range (≥ 20 Å) distance constraints across the trimer of dimers interface. Overall, the work presented here shows that minimally perturbing His-tag mediated dimerization promotes assembly of chemoreceptor arrays with native architecture, and thus enabled us to gain insights into the mode of array assembly and the role of the core functional unit

Negeren of reageren?:Het debat over de aanpak van huilende baby’s in historisch perspectief

For centuries, a crying baby has been problem number one for parents. Present-day advice can roughly be divided between ignoring, to teach the baby that crying doesn’t pay, and responding promptly, to achieve secure attachment. This contradiction in advice can be traced back to a debate that was started in the 1960s between behaviorist Jack Gewirtz and attachment pioneer Mary Ainsworth and which lasted for decades. This debate, of which Gewirtz’s reaction to the groundbreaking findings of Ainsworth’s Uganda and Baltimore studies was only the beginning, is described and analysed. Ainsworth’s studies have been (partly) replicated several times, but up to today, the findings remain contradictory. Analysing and discussing these findings leads to the conclusion that a one-size-fits-all solution for a crying baby is not likely to exist

A tale of four countries: How Bowlby used his trip through Europe to write the WHO report and spread his ideas

Attachment theory, developed by child psychiatrist John Bowlby, is considered a major theory in developmental psychology. Attachment theory can be seen as resulting from Bowlby's personal experiences, his psychoanalytic education, his subsequent study of ethology, and societal developments during the 1930s and 1940s. One of those developments was the outbreak of World War II and its effects on children's psychological wellbeing. In 1950, Bowlby was appointed WHO consultant to study the needs of children who were orphaned or separated from their families for other reasons and needed care in foster homes or institutions. The resulting report is generally considered a landmark publication in psychology, although it subsequently met with methodological criticism. In this paper, by reconstructing Bowlby's visit to several European countries, on the basis of notebook

A tale of four countries: How Bowlby used his trip through Europe to write the WHO report and spread his ideas

Attachment theory, developed by child psychiatrist John Bowlby, is considered a major theory in developmental psychology. Attachment theory can be seen as resulting from Bowlby's personal experiences, his psychoanalytic education, his subsequent study of ethology, and societal developments during the 1930s and 1940s. One of those developments was the outbreak of World War II and its effects on children's psychological wellbeing. In 1950, Bowlby was appointed WHO consultant to study the needs of children who were orphaned or separated from their families for other reasons and needed care in foster homes or institutions. The resulting report is generally considered a landmark publication in psychology, although it subsequently met with methodological criticism. In this paper, by reconstructing Bowlby's visit to several European countries, on the basis of notebooks and letters, the authors shed light on the background of this report and the way Bowlby used or neglected the findings he gathered

Pain during the first year after scoliosis surgery in adolescents, an exploratory, prospective cohort study

Objective: Approximately 50% of adolescents who have undergone scoliosis surgery still experience severe pain one year postoperatively. We explored the postoperative pain trajectory and the potential value of preoperative Thermal Quantitative Sensory Testing (T-QST) as predictor of chronic postsurgical pain after scoliosis surgery. Design: Single-center prospective cohort study in adolescents undergoing scoliosis surgery. Outcomes: Prevalence of chronic postsurgical pain (CPSP) one year after scoliosis surgery and postsurgical pain course during this year. The need for rescue medication and the relationship between pre-operative T-QST, acute pain and CPSP. Results: Thirty-nine patients (mean age 13.9 years; SD 1.9 years) completed the study. One year postoperatively, ten patients (26%) self-reported pain [numeric rating scale (NRS) score ≥ 4]) when moving and two (5%) when in rest. Four of these patients (10.3%) experienced neuropathic pain. The pre-operative cold pain threshold was lower (p = 0.002) in patients with CPSP at 12 months. Preoperative cold and heat pain thresholds were correlated with the number of moderate or severe pain reports (NRS ≥ 4) in the first week postoperatively (r -.426; p = 0.009 and r.392; p = 0.016, respectively). Conclusions: One year after scoliosis surgery, a significant part of patients (26%) still reported pain, some with neuropathic characteristics. Better diagnosis and treatment is needed; our study suggests that T-QST could be further explored to better understand and treat children with this negative outcome.</p